KMID : 0363220100480030206
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Korean Journal of Dermatology 2010 Volume.48 No. 3 p.206 ~ p.208
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Cutaneous Angiosarcoma Presenting as an Alopecia Patch
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Won June-Ho
Won Young-Ho Kim Seong-Jin Lee Seung-Chul Yun Sook-Jung Lee Jee-Bum
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Abstract
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Angiosarcoma is a highly malignant vascular tumor with an incidence of approximately one per ten million. There are three clinical variants; primary angiosarcoma, which occurs on the head and neck in the elderly; angiosarcoma in areas of chronic lymphedema; and post-irradiation angiosarcoma. Primary angiosarcoma shows variable-sized erythematous to violaceous nodules or plaques that become confluent as the lesion progress. We report a case of primary angiosarcoma of the scalp in a 76-year-old man with focal alopecia. Additional immunohistochemical stains showed perifollicular CD34 dominance, which suggested hair follicle-targeted carcinogenesis. (Korean J Dermatol 2010;48(3):206¡208)
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KEYWORD
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Alopecia, Angiosarcoma, CD34
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